ABSTRACT
Adrenocorticotrophin secreting cells are identified in the hypophysis of the brown spiny mouse Mus platythrix by conventional methods of light microscopy. Quantitative data showed that certain smaller acidophilic cells in the pars distalis, under conditions provoking their hypersecretion such as unilateral adrenalectomy and metopirone treatment, increase in number and size from the pre-existing corticotrophs. There is no evidence for the transmigration of these cells from the chromophobes, basophils or any other cell type. The pars intermedia revealed two types of cells of which the type II cells are histochemically identical to adrenocorticotrophin secreting cells of the pars distalis.
ABSTRACT
The degenerative changes in the spermatids as measured by changes in fine structure abnormalities increased with time following injection of Cd2+ into rat testis. The spermatids in the twelve hours group appear as peculiarly club shaped and elongated structures with one or two small but perceptible vacuoles. The subacrosomal area and the space between the nucleus and the middle piece are seen abnormally dilated. In the 30 day group, the central filaments are the most susceptible unit of 9+2 axoneme complex. The plasma membrane, the cytoplasmic matrix, the mitochondria of the middle piece and the fibrous sheath appear shrunken, discontinuous and degenerative.